The SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Virus antigen. The SARS-CoV-2 (COVID-19) 3CL-PRO (NSP5) Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. 3C- like proteinase (NSP5) cleaves the C-terminus of replicase polyprotein at 11 sites (3,4,5). It recognizes substrates containing the core sequence [ILMVF]-Q-:-[SGACN]. It also able to bind an ADP-ribose-1''-phosphate (ADRP) (5)